Ibuprofen
INTRODUCTION
Ibuprofen is a substance from a group of non-steroidal anti-inflammatory drugs. In order for the drug release to be targeted on the basis of pH change (gradual release for up to 30 days), binding to a polymeric carrier is used.
ABSTRACT
Determination of free ibuprofen (CAS 15687-27-1) and ibuprofen bound to a polymer carrier on an ARION® Plus C18, 5.0 µm column (250 mm × 4.6 mm, ARI-5720-LM46). Isocratic elution with ACN/water 70/30 (v/v) + 0.1 % formic acid at 1.0 ml/min, ambient temperature and UV detection at 265 nm. Both forms are separated in a single run of about 7 minutes.
Industries
Pharma & Veterinary Drugs
Category
HPLC columns
Product
Arion Plus C18
Part number
ARI-5720-LM46
Analytes
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- Ibuprofen on polymer carrier CAS number not available
- Ibuprofen CAS number 15687-27-1
