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Astra C18-Hybrid

Hybrid Silica – Where Nature Meets Innovation

Hybrid silica fuses the robustness of inorganic silica with the versatility of organic chemistry, creating a material engineered for superior performance. With enhanced durability and refined surface functionality, hybrid silica enables smarter, longerlasting solutions across advanced industrial and technological applications. High density end-capping together with fully hybrid particles synthetised from scratch deliver superior high alkaline durability compared to partially hybrid solutions.

KEY BENEFITS

  • Fully hybrid particles for a wide pH range from 1 to 12
  • C18 with improved selectivity for basic compounds
  • Narrow peaks at low pH – significant reduction in acid hydrolysis of the C18 ligand
  • Enhanced method development flexibility
  • Double end-capping with unique surface treatment for superior peak shape
  • Stability in 100% aqueous mobile phase, even at elevated pH
Pore Size 100 A
LC Phases C18-Hybrid
Particle Type Fully Porous
LC Technique HPLC/UHPLC

Brochures

Other Documents

Product name ID Particle Size LC length Product code
ASTRA® C18-HYBRID HPLC column, 3.0 µm 100 mm × 3.0 mm 3 mm 3 µm 100 mm AST-6016-II30
ASTRA® C18-HYBRID HPLC column, 3.0 µm 100 mm × 4.6 mm 4.6 mm 3 µm 100 mm AST-6016-II46
ASTRA® C18-HYBRID HPLC column, 3.0 µm 150 mm × 3.0 mm 3 mm 3 µm 150 mm AST-6016-IK30
ASTRA® C18-HYBRID HPLC column, 3.0 µm 150 mm × 4.6 mm 4.6 mm 3 µm 150 mm AST-6016-IK46
ASTRA® C18-HYBRID HPLC column, 3.0 µm 250 mm × 4.6 mm 4.6 mm 3 µm 250 mm AST-6016-IM46
ASTRA® C18-HYBRID HPLC column, 3.0 µm 50 mm × 4.6 mm 4.6 mm 3 µm 50 mm AST-6016-IG46
ASTRA® C18-HYBRID HPLC column, 5.0 µm 100 mm × 4.6 mm 4.6 mm 5 µm 100 mm AST-6016-LI46
ASTRA® C18-HYBRID HPLC column, 5.0 µm 150 mm × 4.6 mm 4.6 mm 5 µm 150 mm AST-6016-LK46
ASTRA® C18-HYBRID HPLC column, 5.0 µm 250 mm × 4.0 mm 4 mm 5 µm 250 mm AST-6016-LM40
ASTRA® C18-HYBRID HPLC column, 5.0 µm 250 mm × 4.6 mm 4.6 mm 5 µm 250 mm AST-6016-LM46
ASTRA® C18-HYBRID HPLC column, 5.0 µm 50 mm × 4.6 mm 4.6 mm 5 µm 50 mm AST-6016-LG46

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